Common side effects of Quaaludes include:

• dizziness
• nausea
• vomiting
• diarrhea
• abdominal cramps
• fatigue
• itching
• rashes
• sweating
• dry mouth
• tingling sensation in arms and legs
• seizures
• reduced heart rate
• slowed breathing (respiration).

Quaaludes can also cause erectile dysfunction and difficulty achieving orgasms. At high doses it can cause mental confusion and loss of muscle control (ataxia).

As with most drugs of abuse, it was found that Quaaludes users made poor decisions and lacked normal abilities under its influence. Driving skills of Quaalude users were often impaired and lead to fatal car accidents.

This is not a complete list of side effects and others may occur.