In 1972, Quaaludes were one of the most frequently prescribed sedatives in United States.

In prescribed doses, Quaaludes promotes relaxation, sleepiness and sometimes a feeling of euphoria (happiness, calmness). It causes a drop in blood pressure and slows the pulse rate. These properties are the reason why it was initially thought to be a useful sedative and anxiolytic.

It became a recreational drug due to its euphoric ("high") effect. Quaaludes were a popular drug of abuse during much of the 1970s, even though both the US and Britain tightened control around their use and dispensing.